The publication of Uncle Tom's Cabin; or, Life Among the Lowly by Harriet Beecher Stowe. It was the best-selling novel of the 19th century and the second best-selling book of that century, following the Bible. It is credited with helping fuel the abolitionist cause in the 1850s. In recent years, the negative associations with Uncle Tom's Cabin have, to an extent, overshadowed the historical impact of the book as a "vital antislavery tool. [Wikipedia]
Harriet Beecher Stowe was an ancestor of Ellen "Mother" Beecher who was a grandmother of Hand of the Cause of God Dorothy Baker.